It is entirely up to you. There is no etiquette rule covering this issue. However, if this is someone that you talk to often, tell him that you know that he cannot attend, but wish that he could so he won't feel left out.
Because I didn't want to simply send wedding announcements to some family members, I actually included a handwritten note in a few of my invitations for those family members living in other states. It just seemed as if I was including them in my happy day.